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Using two separate drugs to shed weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the those who go through it you should err to the side of caution and permit the FDA do its job and demand some study be done in order that the public is aware of the side effects and hazards of the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say almost anything to keep people on the medications. Researchers discovered that participants using this drug for any year, dropped a few pounds within 4 weeks and have kept the weight off through the entire 56 weeks in the study. Contrave is a combination from the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of several active ingredient, which may make them more effective and safer. Combo-pilling will be the newest fad or also the newest into the future under scrutiny and for that reason it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is now popular will be the fact that since right now there are no long term prescription slimming capsules that have been authorized by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug can also raise hypertension and pulse rate, and really should not be used in those with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not be used in patients with uncontrolled high blood pressure levels, as well as by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients which has a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking. BioCorRx, Inc.'s naltrexone implant is no bigger than a thumb which is inserted under the patient's skin by having a 30-minute, minimally invasive outpatient procedure made by a health care professional. The implant is administered as part of BioCorRx, Inc.'s Start Fresh Program which is distributed in numerous states by independent rehabilitation facilities.